Endocrinology and Endocrine System
Association of Type 2 Diabetes Mellitus and Thyroid Disease: The Systematic Review and Meta Analysis
Abstract
Introduction: Patients with Type 2 Diabetes Mellitus (T2DM) are more susceptible to thyroid disorders. Many diabetic patients exhibit features of thyroid dysfunction over a period of time. This study was designed to collect data on the association between T2DM and thyroid disease.
Materials and methods: This study is a systematic review and meta-analysis. Source of this study data comes from literature obtained through the internet in the form of research results published on the internet, both in Cochrane, PubMed, Googlescholar, and other journal databases. We searched for the keywords “blood glucose” and “thyroid disease”. The inclusion criteria of the research that will be included are studies that examine the relationship between thyroid disease and blood glucose levels, with adult research subjects (not animal studies), research conducted within the last ten years and using primary data.
Results: We found several relevant journals or articles related to the relationship between thyroid disease and blood glucose levels. The search results in the Pubmed journal database, we found four journal that discusses the relationship between thyroid disease and blood glucose levels. A Google scholar search shows two studies relevant to this study.
Conclusion: The findings of this systematic review showed that mircroRNA functions as a tumor suppressor or a promoter in cholangiocarcinoma.