Biotransformation is the process by which a substance changes from one chemical to another (transformed) by a chemical reaction within the body. Metabolism or metabolic transformations are terms frequently used for the biotransformation process. However, metabolism is sometimes not specific for the transformation process but may include other phases of toxicokinetics.
Biotransformation is vital to survival because it transforms absorbed nutrients (food, oxygen, etc.) into substances required for normal body functions. For some pharmaceuticals, it is a metabolite that is therapeutic and not the absorbed drug.
For example, phenoxybenzamine, a drug given to relieve hypertension caused by pheochromocytoma, a kind of tumor, is biotransformed into a metabolite, which is the active agent.
Biotransformation also serves as an important defense mechanism since toxic xenobiotics and body wastes are converted into less harmful substances and substances that can be excreted from the body.
Last Updated on: Nov 23, 2024List of Open Access Journals View More
Journal of Oncology and Cancer Research
Journal of Oncology and Cancer Research provides a unique platform for all the academicians and professionals to share their knowledge, laboratory findings, discussions which in-turn accelerates the further research in the field of cancer. JOCR manuscripts undergo rigorous...View More
Journal of Environmental and Pollution
JEP is a scholarly open access peer-reviewed journal aim to publish be valuable source of information both experimental and theoretical in the field of environmental issues and Pollution and its applications...View More
Endocrinology and Endocrine System
Endocrinology and Endocrine System is an Open Access journal which aims to develop knowledge and to share the information freely by making them available through online without any restrictions or any other subscriptions to researchers worldwide and also to the readers globally...View More
Journal of Molecular Genetics and Gene Research
Journal of Molecular Genetics and Gene Research is a peer reviewed scientific journal known for rapid dissemination of high-quality research. It serves the International Scientific Community with its standard research publications. This journal is using Online Manuscript Management system...View More
Department of Electrical Engineering: Current Research
DEECR welcomes authors to contribute current research and reports, Experimental studies, Review articles, Short communication, Editorial, Letter to Editor, Survey Reports submission of manuscripts related to Signal Processing, Material Science, Microelectronics, Electronic materials, Power System Protection, DC Power Converter, C Power Converter, Electrophysics and its applications, Electromagnetism, etc....View More
Journal of Medical Sciences and Health Care Research
Journal primary objective is to provide research and applications related to Medical & Health Sciences. This journal strives to serve a diverse readership by publishing articles in a wide range of topics. This journal will welcome articles from the field of all specialities medical science that includes feilds like medicine...View More