Biotransformation is the process by which a substance changes from one chemical to another (transformed) by a chemical reaction within the body. Metabolism or metabolic transformations are terms frequently used for the biotransformation process. However, metabolism is sometimes not specific for the transformation process but may include other phases of toxicokinetics.
Biotransformation is vital to survival because it transforms absorbed nutrients (food, oxygen, etc.) into substances required for normal body functions. For some pharmaceuticals, it is a metabolite that is therapeutic and not the absorbed drug.
For example, phenoxybenzamine, a drug given to relieve hypertension caused by pheochromocytoma, a kind of tumor, is biotransformed into a metabolite, which is the active agent.
Biotransformation also serves as an important defense mechanism since toxic xenobiotics and body wastes are converted into less harmful substances and substances that can be excreted from the body.
Last Updated on: Jan 22, 2025List of Open Access Journals View More
Academic Journal of Chemical Engineering
AJCE is a scholarly open access peer-reviewed journal aim to publish be valuable source of information in field of Chemical science, biophysics, engineering, environmental science, medicine, physical science current research in the field....View More
Clinical Trials and Medical Case Reports
Clinical trials and Medical Case reports is an open access peer reviewed journal. It publishes Clinical trials, Medical case reports and Medical images from all fields of medicine in all orders by which medicinal services experts, specialists and others can easily understand the disease conditions...View More
Health and Preventive Medicine Journal
Health and Preventive Medicine Journal (HPMJ) is a scholarly open access peer-reviewed journal aim to publish be valuable source of information both experimental and theoretical in field of Health science, Epidemiology, Health management and Preventive medicine...View More
Dermatology Case Reports: Open Access Journal
DCROAJ welcome authors to contribute current research and reports, clinical studies, review articles, short communication, editorial, letter to editor, survey reports submission of manuscripts related to devices in dermatology, dermatology studies, new technology in dermatology, biological materials, venereology, leprology etc....View More
Journal of Oncology and Cancer Research
Journal of Oncology and Cancer Research provides a unique platform for all the academicians and professionals to share their knowledge, laboratory findings, discussions which in-turn accelerates the further research in the field of cancer. JOCR manuscripts undergo rigorous...View More
International Journal of Biomedical Science and Research
International Journal of Biomedical Science and Research is an Open Access, peer-reviewed, academic journal that provides an area to share the information by medical scientists and researchers on the topics of biomedical science. Biomedical Science is the field of study that focuses on the areas of biology...View More