Genotoxic chemicals exert their adverse effect through interaction with genetic material (DNA) of cells. Genotoxicity tests are designed to detect drugs which can induce genetic damage directly or indirectly by various mechanisms of action. Compounds identified as genotoxic in these tests have the potential to be human carcinogens and/or mutagens, and ultimately may induce cancer and/or heritable defects.
Genotoxicity testing of new chemical entities is an integral part of the drug development process and is a regulatory requirement prior to the approval of new drugs. By identifying genotoxicity at an early stage in drug discovery rather than during regulatory assessment, the likelihood of late stage failures is reduced.
Last Updated on: Dec 22, 2024List of Open Access Journals View More
International Journal of Quantum Technologies
International Journal of Quantum Technologies publishes original, current research, novel methods, advancing research on quantum optics, modern quantum physics, quantum computing, Quantum electromechanical systems and quantum metrology, etc. strategies that will drive positive change in the worldwide....View More
Journal of Medical Sciences and Health Care Research
Journal primary objective is to provide research and applications related to Medical & Health Sciences. This journal strives to serve a diverse readership by publishing articles in a wide range of topics. This journal will welcome articles from the field of all specialities medical science that includes feilds like medicine...View More
International Journal of Economic Research Updates
Reviews in Pharmacy and Pharmaceutical sciences is a peer-reviewed scholarly journal that aims to publish high quality research on Pharmacology and Toxicology, Pharmaceutical Chemistry, Pharmaceutical Analysis and Quality Assurance, Pharmaceutics, Hospital and Clinical Pharmacy...View More
Health and Preventive Medicine Journal
Health and Preventive Medicine Journal (HPMJ) is a scholarly open access peer-reviewed journal aim to publish be valuable source of information both experimental and theoretical in field of Health science, Epidemiology, Health management and Preventive medicine...View More
Academic Journal of Chemical Engineering
AJCE is a scholarly open access peer-reviewed journal aim to publish be valuable source of information in field of Chemical science, biophysics, engineering, environmental science, medicine, physical science current research in the field....View More
Dermatology Case Reports: Open Access Journal
DCROAJ welcome authors to contribute current research and reports, clinical studies, review articles, short communication, editorial, letter to editor, survey reports submission of manuscripts related to devices in dermatology, dermatology studies, new technology in dermatology, biological materials, venereology, leprology etc....View More