Genotoxic chemicals exert their adverse effect through interaction with genetic material (DNA) of cells. Genotoxicity tests are designed to detect drugs which can induce genetic damage directly or indirectly by various mechanisms of action. Compounds identified as genotoxic in these tests have the potential to be human carcinogens and/or mutagens, and ultimately may induce cancer and/or heritable defects.
Genotoxicity testing of new chemical entities is an integral part of the drug development process and is a regulatory requirement prior to the approval of new drugs. By identifying genotoxicity at an early stage in drug discovery rather than during regulatory assessment, the likelihood of late stage failures is reduced.
Last Updated on: Jan 22, 2025List of Open Access Journals View More
Journal of Oncology and Cancer Research
Journal of Oncology and Cancer Research provides a unique platform for all the academicians and professionals to share their knowledge, laboratory findings, discussions which in-turn accelerates the further research in the field of cancer. JOCR manuscripts undergo rigorous...View More
Endocrinology and Endocrine System
Endocrinology and Endocrine System is an Open Access journal which aims to develop knowledge and to share the information freely by making them available through online without any restrictions or any other subscriptions to researchers worldwide and also to the readers globally...View More
Academic Journal of Chemical Engineering
AJCE is a scholarly open access peer-reviewed journal aim to publish be valuable source of information in field of Chemical science, biophysics, engineering, environmental science, medicine, physical science current research in the field....View More
International Journal of Economic Research Updates
Reviews in Pharmacy and Pharmaceutical sciences is a peer-reviewed scholarly journal that aims to publish high quality research on Pharmacology and Toxicology, Pharmaceutical Chemistry, Pharmaceutical Analysis and Quality Assurance, Pharmaceutics, Hospital and Clinical Pharmacy...View More
Review of Cell Science Journal
RCSJ welcome researchers, pharma companies, professors, scientists, biologists, biotechnologists, immunologists, stem cell researchers, clinical scientists, molecular biologists to contribute current research work to the scientific world....View More
Dermatology Case Reports: Open Access Journal
DCROAJ welcome authors to contribute current research and reports, clinical studies, review articles, short communication, editorial, letter to editor, survey reports submission of manuscripts related to devices in dermatology, dermatology studies, new technology in dermatology, biological materials, venereology, leprology etc....View More