Immunogenicity is the ability of a foreign substance, such as an antigen, to provoke an immune response in the body of a human or other animal. In other words, immunogenicity is the ability to induce a humoral and/or cell-mediated immune responses.
Distinction is made between wanted and unwanted immunogenicity:
Wanted immunogenicity is typically related with vaccines, where the injection of an antigen (the vaccine) provokes an immune response against the pathogen (virus, bacteria), protecting the organism from future exposure. Vaccine development is a complex multi-step process, with immunogenicity being at the center of vaccine efficacy.
Unwanted immunogenicity is an immune response by an organism against a therapeutic antigen (ex. recombinant protein, or monoclonal antibody). This reaction leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects.
Last Updated on: Nov 23, 2024List of Open Access Journals View More
International Journal of Biomaterials and Tissue Engineering
IJBTE is a scholarly open access peer-reviewed journal aim to publish be valuable source of information both experimental and theoretical in field of Tissue science, Health science, Regenerative medicine, Engineering and use of devices and biomaterial for disease diagnosis in biological system....View More
Journal of Molecular Genetics and Gene Research
Journal of Molecular Genetics and Gene Research is a peer reviewed scientific journal known for rapid dissemination of high-quality research. It serves the International Scientific Community with its standard research publications. This journal is using Online Manuscript Management system...View More
International Journal of Catalysis and Chemical Engineering
International Journal of Catalysis and Chemical Engineering (IJCCE) is a scholarly open access per-reviewed journal aim to publish be valuable source of information in field of Chemical Engineering, Catalysis, Catalytic Materials & Mechanisms, Nanocatalysis....View More
Journal of Medical Sciences and Health Care Research
Journal primary objective is to provide research and applications related to Medical & Health Sciences. This journal strives to serve a diverse readership by publishing articles in a wide range of topics. This journal will welcome articles from the field of all specialities medical science that includes feilds like medicine...View More
Public Health and Epidemiology: Open Access Journal
PHEOAJ is a scholarly open access peer-reviewed journal aim to publish be valuable source of information both experimental and theoretical in the field of Public health, Epidemiology, Health care system...View More