Immunogenicity is the ability of a foreign substance, such as an antigen, to provoke an immune response in the body of a human or other animal. In other words, immunogenicity is the ability to induce a humoral and/or cell-mediated immune responses.
Distinction is made between wanted and unwanted immunogenicity:
Wanted immunogenicity is typically related with vaccines, where the injection of an antigen (the vaccine) provokes an immune response against the pathogen (virus, bacteria), protecting the organism from future exposure. Vaccine development is a complex multi-step process, with immunogenicity being at the center of vaccine efficacy.
Unwanted immunogenicity is an immune response by an organism against a therapeutic antigen (ex. recombinant protein, or monoclonal antibody). This reaction leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects.
Last Updated on: Jan 22, 2025List of Open Access Journals View More
Reviews in Pharmacy and Pharmaceutical Sciences
Reviews in Pharmacy and Pharmaceutical sciences is a peer-reviewed scholarly journal that aims to publish high quality research on Pharmacology and Toxicology, Pharmaceutical Chemistry, Pharmaceutical Analysis and Quality Assurance, Pharmaceutics, Hospital and Clinical Pharmacy...View More
Journal of Next Generation Materials Engineering Research
JNGMER welcome authors to contribute current research and reports manuscripts related to Thermal Engineering, Environmental Catalysis, Reaction kinetics, Physical Chemistry, Catalysis & Adsorption, Processes of Heat, Momentum Transfer, Nanocatalysis, Reactor Engineering, Reactor Designs and Materials, and Thermodynamic Engineering, etc...View More
Department of Electrical Engineering: Current Research
DEECR welcomes authors to contribute current research and reports, Experimental studies, Review articles, Short communication, Editorial, Letter to Editor, Survey Reports submission of manuscripts related to Signal Processing, Material Science, Microelectronics, Electronic materials, Power System Protection, DC Power Converter, C Power Converter, Electrophysics and its applications, Electromagnetism, etc....View More
International Journal of Biomaterials and Tissue Engineering
IJBTE is a scholarly open access peer-reviewed journal aim to publish be valuable source of information both experimental and theoretical in field of Tissue science, Health science, Regenerative medicine, Engineering and use of devices and biomaterial for disease diagnosis in biological system....View More
Clinical Trials and Medical Case Reports
Clinical trials and Medical Case reports is an open access peer reviewed journal. It publishes Clinical trials, Medical case reports and Medical images from all fields of medicine in all orders by which medicinal services experts, specialists and others can easily understand the disease conditions...View More
Journal of Oncology and Cancer Research
Journal of Oncology and Cancer Research provides a unique platform for all the academicians and professionals to share their knowledge, laboratory findings, discussions which in-turn accelerates the further research in the field of cancer. JOCR manuscripts undergo rigorous...View More