A local anesthetic is a medication that causes the absence of pain sensation. When it is used on specific nerve pathways, paralysis also can be achieved. Clinical LAs belong to one of two classes: aminoamide and aminoester local anesthetics. Synthetic LAs are structurally related to cocaine. LAs act by reversibly blocking the sodium channels of nerve fibers, thereby inhibiting the conduction of nerve impulses. All local anesthetics, with the exception of cocaine, are vasodilators. Vasodilation occurs via direct relaxation of peripheral arteriolar smooth muscle fibers. Greatervasodilator activity of a local anesthetic leads to faster absorption and, thus, shorter duration of action.
Last Updated on: Nov 06, 2024List of Open Access Journals View More
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Endocrinology and Endocrine System is an Open Access journal which aims to develop knowledge and to share the information freely by making them available through online without any restrictions or any other subscriptions to researchers worldwide and also to the readers globally...View More
Department of Electrical Engineering: Current Research
DEECR welcomes authors to contribute current research and reports, Experimental studies, Review articles, Short communication, Editorial, Letter to Editor, Survey Reports submission of manuscripts related to Signal Processing, Material Science, Microelectronics, Electronic materials, Power System Protection, DC Power Converter, C Power Converter, Electrophysics and its applications, Electromagnetism, etc....View More
International Journal of Catalysis and Chemical Engineering
International Journal of Catalysis and Chemical Engineering (IJCCE) is a scholarly open access per-reviewed journal aim to publish be valuable source of information in field of Chemical Engineering, Catalysis, Catalytic Materials & Mechanisms, Nanocatalysis....View More
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Journal of Oncology and Cancer Research provides a unique platform for all the academicians and professionals to share their knowledge, laboratory findings, discussions which in-turn accelerates the further research in the field of cancer. JOCR manuscripts undergo rigorous...View More
International Journal of Economic Research Updates
Reviews in Pharmacy and Pharmaceutical sciences is a peer-reviewed scholarly journal that aims to publish high quality research on Pharmacology and Toxicology, Pharmaceutical Chemistry, Pharmaceutical Analysis and Quality Assurance, Pharmaceutics, Hospital and Clinical Pharmacy...View More